Automated blood sampling and the 3Rs
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چکیده
Automated blood sampling (ABS) systems have been increasingly employed in biomedical research since the mid-1990s for use in pharmacokinetic, safety pharmacology, metabolism, biomarker and other studies in industry and academia. Originally conceived with the purpose of reducing animal use and stress, this article reviews the contribution of ABS systems to the 3Rs concept of Russell and Burch (1).
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